Swiss Chicken Casserole Recipe

There's nothing quite like the creamy, cheesy comfort of Swiss Chicken Casserole on a chilly evening. With tender chicken breasts smothered in a rich, flavorful sauce and topped with crispy, buttery stuffing, this dish is the ultimate cozy dinner.

I first discovered this recipe when I was searching for a way to use up leftover Swiss cheese, and it quickly became a family favorite. It's easy to throw together, packed with flavor, and perfect for busy weeknights or potluck gatherings.

Why You'll Love This Swiss Chicken Casserole

If you're looking for a quick, comforting meal that the whole family will love, this Swiss Chicken Casserole is the answer. With simple ingredients and minimal prep, it’s perfect for those nights when you want something delicious without spending hours in the kitchen.

It's incredibly easy to make. You only need a handful of pantry staples, and everything comes together in just one baking dish—less cleanup means more time to relax!

The flavors are rich and comforting. The combination of Swiss cheese, creamy sauce, and seasoned stuffing creates a perfect balance of cheesy, savory goodness with a slight crunch on top.

It's a great make-ahead dish. You can prep everything in advance and simply pop it in the oven when you're ready to eat. It's a lifesaver for busy weeknights!

Perfect for potlucks and family dinners. This casserole is always a crowd-pleaser, making it ideal for holidays, gatherings, or meal trains for a friend in need.

Ingredients Notes

The beauty of this Swiss Chicken Casserole lies in its simple yet flavorful ingredients. Each one plays a key role in creating a dish that’s both creamy and satisfying.

• Chicken Breasts: Boneless, skinless chicken breasts work best for this casserole. You can also use rotisserie chicken for an even easier version.
• Swiss Cheese: The star of the show! Swiss cheese melts beautifully and adds a nutty, slightly tangy flavor that complements the creamy sauce.
• Cream of Chicken Soup: This acts as the base for the creamy sauce. You can use cream of mushroom soup if you prefer a slightly earthier taste.
• Sour Cream: Adds a rich, tangy creaminess to the dish. For a lighter option, use Greek yogurt instead.
• Stuffing Mix: A buttery, seasoned stuffing mix creates the perfect crispy topping. Stove Top brand works well, but homemade stuffing is also an option.
• Butter: Helps crisp up the stuffing, adding a delicious, golden-brown crunch.

Special Equipment: You’ll need a 9x13-inch baking dish to ensure even cooking and a spoon or whisk to mix the sauce.

How To Make This Swiss Chicken Casserole

Making this Swiss Chicken Casserole couldn’t be easier. With just a few steps, you’ll have a warm, comforting meal ready to go!

Step 1: Preheat and Prep
Preheat your oven to 350°F (175°C) and lightly grease a 9x13-inch baking dish. This helps prevent sticking and makes cleanup easier.

Step 2: Arrange the Chicken and Cheese
Lay the chicken breasts flat in the baking dish. If they’re thick, you can slice them in half lengthwise for even cooking. Then, place a slice of Swiss cheese over each piece of chicken.

Step 3: Make the Creamy Sauce
In a medium bowl, whisk together cream of chicken soup and sour cream until smooth. Spread this mixture evenly over the chicken, covering it completely.

Step 4: Add the Stuffing
Sprinkle the stuffing mix evenly over the top of the casserole. Drizzle melted butter over the stuffing to help it brown and crisp up beautifully in the oven.

Step 5: Bake Until Bubbly
Cover the dish with foil and bake for 35 minutes. Then, remove the foil and bake for another 10-15 minutes, until the top is golden and crispy and the chicken is cooked through (internal temp of 165°F).

Step 6: Serve and Enjoy!
Let the casserole rest for 5 minutes before serving. This allows the sauce to thicken slightly and makes serving easier.

Storage Options

If you have leftovers (which isn’t likely!), this casserole stores well and tastes just as delicious the next day.

Refrigerate: Store in an airtight container for up to 3 days. Reheat in the oven at 350°F until warm or microwave in 30-second intervals.

Freeze: You can freeze the uncooked casserole by assembling everything except the stuffing. Wrap tightly in plastic wrap and foil, and freeze for up to 3 months. When ready to bake, thaw overnight in the fridge, add stuffing, and bake as directed.

Make-Ahead Tip: Assemble the casserole the night before and refrigerate. When ready to bake, let it sit at room temperature for 20 minutes before putting it in the oven.

Variations and Substitutions

One of the best things about Swiss Chicken Casserole is how easily you can customize it!

• Use a Different Cheese: If Swiss cheese isn’t your favorite, try provolone, mozzarella, or cheddar for a different flavor profile.
• Try a Different Protein: Swap out the chicken for turkey, ham, or even cooked ground beef for a fun twist.
• Make it Gluten-Free: Use a gluten-free cream soup and stuffing mix to make this dish friendly for gluten-sensitive eaters.
• Add Veggies: Mix in broccoli, mushrooms, or spinach for a more well-rounded meal.
• Make It Lighter: Swap out sour cream for Greek yogurt and use a reduced-fat cheese for a healthier version.

This casserole is so versatile—feel free to get creative with what you have on hand!

Print